C-Reactive protein in community acquired pneumonia

Muthanna Medical Journal
Volume 5, Issue 1, June 2018, Pages 12-20
http://dx.doi.org/10.18081/2410-4590/2018-12-20

Research Article

Mohammed Abed Abdulhussein¹, Haydar Jawad Al-Jobourim, Ali Ameer

* Correspondence author: mmssaalions@yahoo.com
¹Kufa University/ College of Medicine/Department of Medicine
Received 04 January 2018, Accepted 12 March 2018, Available online 22 March 2018.
This is article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright © 2018MA

Abstract

C-reactive protein (CRP) is an acute phase protein synthesized by hepatocytes. In response to infection or tissue inflammation, CRP production is rapidly stimulated by cytokines, particularly interleukin (IL)-6, IL-1 and tumor necrosis factor. The aim of the present study is to evaluate the prognostic value of CRP levels at admission as an indicator of the severity or complication of CAP. Fifty patients with primary diagnosis of community-acquired pneumonia during March  2013 to February  2014. A 25 patients were males and 25 females. The CRP measured by CRP-latex Slide agglutination method. Also patient underwent chest-x ray and patients were  categorized into   patients with CRP ≥ 100 mg/L and  CRP < 100 mg/L22, and the complications (pleural effusion and lung abscess) were correlated to possible risk factors (HT, DM) and smoking. There is a significant increase in complication of CAP in patients with high CRP level  (CRP ≥ 100 mg/L) ,so that CRP is highly sensitive, specific and accurate test to predict complication in CAP.  The CRP affected by gender (female), age and diabetes mellitus in patient with CAP. There is  no significant correlations between CRP level and  smoking and hypertension in patient with CAP.

Key words: C-reactive protein (CRP); CAP; Diabetes Mellitus

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