Detection the biological activity of aqueous extract of Shamar plant seeds Foeniculum vulgare Mill

Muthanna Medical Journal
Volume 3, Issue 1, June 2016, Pages 49-55

 

Research Article                                                                         

Talib F. Abbas*

*Corrospondance author: tlb_abbas77@yahoo.com
College of pharmacy, Muthanna University.  Received 12 October 2015, Accepted 29 May 2016, Available online 28 June  2016.
This is article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright © 2016 TA


Abstract

Unfortunately, many type of chemical drugs approved their unsafely, after period of use, it have been withdrawn from markets. Otherwise, herbal medicine wide spread in using and application, with some modification if it's necessary. Shamar herbs Foeniculum vulgare Mill, is a herbaceous plant of the family Umbillflorae, native to the Mediterranean, have a WHO recommendation, is a main component of many manufactured drugs in pediatrics. It is commonly known as fennel has been in medicine as analgesic, digestive, diuretic, lactigenous, anti-inflammatory, anti­- spasmodic agent. Crude extract for the verification of biological activity was prepared from seeds bought in the markets. The antimicrobial activity was determined by paper disc diffusion test and minimum inhibitory concentration MIC. The tested microorganisms were clinical isolates obtained from bacteriology sector of Al- Samawa hospital for women and children, It had been evaluated its biological activity in 3 different model of microorganism (E. coli, Klepsiella spp. and Pseudomonas spp.). Results of evaluation approved the biological activity of Foeniculum vulgare Mill as bactericide effect. The MIC show quantity and quality effects of fennel on the Microorganism model, The Coliform inhibited by the lower concentrations gradient, Klebsiella spp. had affected by higher doses, while, the Pseudomonas spp. did not show any change for all concentrations gradient. Therefore, shamar ( Fennel) extract had a pharmacological character in treat many GIT, respiratory infection, in addition to its favor effect in nursing and lactation. 

Keywords: Fennel; Antimicrobial activity; Foeniculum vulgare 

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