The Effect of pulmonary tuberculosis and short course treatment on some hormones of patients women

Muthanna Medical Journal
Volume 3, Issue 2, December 2016, Pages 139-146                                
http://dx.doi.org/10.18081/2410-4590/2016-139-146

Research Article

Duaa Hamad Hamza, Kadam Mohammad Sabee¹*

¹Department of Biology/College of Science/Al-Muthanna University/Samawah, Iraq
Received 11 August 2016, Accepted 28 November 2016, Available online 18 December 2016
This is article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright © 2016MA

Abstract

The objective of this study was to investigate the changes that occurred on some hormones of patients women with pulmonary tuberculosis and the side effects of anti-tuberculosis drugs which used in Directed Observed Treatment Short course (DOTS) on some hormones. The study included follow-up (100) cases from the women who suffer from Pulmonary tuberculosis disease (before treatment ,after two months of treatment and after six months of treatment) , and the results were compared to control group composed of (100) healthy women , the patients groups and control group ages were ranged (21-60)years old .The results of this study showed non-significant differences at (p>0.05) in TSH levels of all groups patients as compared between them or as compared with control. also the results indicated non-significant differences at (p>0.05) in T4 and T3 levels of before treatment patients group as compared with control but the results indicated a significant decrease at (P<0.05) in T4 and T3 levels of after treatment patients groups (after two months of treatment group and after six months of treatment group) as compared with the control group or as compared with before treatment patients group. Also the results showed a significant decrease at (P<0.05) in T4 and T3 levels of after six months of treatment patients group as compared with after two months of treatment patients group. Our results indicated a significant decrease at(P<0.05) in EPO level of before treatment patients group as compared with control group but the results recorded non-significant differences at (p>0.05) in EPO levels of after treatment patients groups (after two months of treatment group and after six months of treatment group) as compared with control group. Also the results recorded non-significant differences at (p>0.05) in EPO levels of after six months of treatment patients group as compared with after two months of treatment patients group.

Keywords: Pulmonary tuberculosis, Short course treatment, TSH, T4, T3, EPO, ELISA

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