Hussein Aziz Naser¹*, Aedha F Ibrahem2,Hashim A Hashim3
Basophil is one of the granulocytes leukocytes that has many functions, one of them is the secretion of heparin. The aim study is investigated the correlate the basophilic count with the low endogenous heparin and thrombosis in the deep veins and the thromboembolism. A cross-sectional study conducted at Al Sader Medical City (radiology unit, Doppler unit study and emergency room) during the period from December 2015 to February 2017 included 203 patients with diagnosis of deep vein thrombosis (DVT) by Ultrasonic Doppler study or pulmonary embolism (PE) by CT pulmonary angiography. A group of 205 subjects without evidence of DVT were used as a control. One hundred sixty seven patients (82.3%) had DVT for first time, while 14 (6.9%) had recurrent DVT, and 22 (10.8%) had PE. The total male number has thromboembolism disease 52 but total female number is 151 with a male to female ratio was 1: 2.9. At current study founded the basophil percent and basophil count in patient with thromboembolism disease was decreased than normal value, The mean basophil percent in thromboembolism disease was 0.35% ± 0.28% while mean basophil count is 30 ± 26, It had been significantly found that basophil percent and basophilic cell count had a strong association with thromboembolism. Basophil percent had a sensitivity of 82%, specificity 79.5% and accuracy of 80.8%. The corresponding values of these parameters for the basophil count were 85%, 73.2% and 79.1%. In conclusion; both low basophil percent and the basophilic count are significantly associated with DVT, recurrent DVT and PE.
Keywords: Basophil; Thrombosis; Pulmonary angiography
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